Allopurinol
= Prescription Required 
= Generic Equvalent
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Allopurinol 100mg Tablets
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Allopurinol 300mg Tablets
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Allopurinol Prescription Drug Information
Allopurinol (By mouth)
Allopurinol (al-oh-PURE-i-nol)
Treats gout and some kinds of kidney stones. Lowers the amount of uric acid in blood.
Brand Name(s):Zyloprim
There may be other brand names for Allopurinol.
When Allopurinol Should Not Be Used:
You should not use Allopurinol if you have ever had an allergic reaction to allopurinol.
How to Use Allopurinol:
Tablet, Capsule
- Take Allopurinol exactly as your doctor ordered.
- Even if you think the medicine is not working, KEEP TAKING THE ALLOPURINOL, even if you are taking other medicines for gout attacks. The attacks should become shorter and less severe after you take allopurinol for several months.
- Drink 10 to 12 full glasses of liquids each day unless directed differently by your doctor.
- You may take the medicine after meals to avoid stomach upset.
If a dose of Allopurinol is missed:
- Take as soon as possible except when it is close to the time for your next dose.
- If almost time for next dose, skip the missed dose and return to your regular dosing schedule.
- You should not use two doses at the same time.
How to Store and Dispose of Allopurinol:
- Store at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine out of the reach of children
Drugs and Foods to Avoid While Taking Allopurinol:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are taking blood thinners (such as Coumadin®), diuretics (such as hydrochlorothiazide), ampicillin, amoxicillin, cyclosporine, azathioprine (Imuran®), or mercaptopurine (Purinethol®).
- Avoid taking large doses of vitamin C.
- To help prevent gout attacks, avoid beer, wine, alcoholic drinks, and purine-rich foods, such as anchovies, sardines, liver, kidney, lentils, and sweetbreads.
Warnings While Using Allopurinol:
- Check with your doctor before taking Allopurinol if you have diabetes, high blood pressure, heart failure, seizures, kidney disease, liver disease, cancer or other medical problems.
- If you are pregnant or breastfeeding, talk with your doctor before taking Allopurinol.
- Allopurinol may make you drowsy. Be careful when driving a car or using machinery.
- Stop using allopurinol and call your doctor right away if you notice a skin rash, pain when you use the bathroom (urinate), blood in your urine, irritation of your eyes, or swelling of your lips or mouth.
- Your doctor may prescribe another medicine, colchicine, when you start using allopurinol. Be sure to get an information sheet about colchicine also.
Possible Side Effects While Using Allopurinol:
Call your doctor right away if you notice any of these side effects:
- Burning or peeling of skin
- Chills, fever, or sore throat
- Joint pain or muscle aches
- Nausea and vomiting along with a skin rash
- Skin rash, redness, itching or hives
- Trouble breathing
- Yellow skin or eyes
If you notice these less serious side effects while taking Allopurinol, talk with your doctor:
- Drowsiness
- Headache
- Nausea, vomiting, or diarrhea
If you notice other side effects that you think are caused by Allopurinol, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
