Fluconazole
= Prescription Required 
= Generic Equvalent
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Fluconazole 100mg Tablets
Manufactured by Ivax
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Fluconazole 150mg Capsules
Manufactured by Apotex Incorporated
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Fluconazole Prescription Drug Information
Fluconazole (By mouth)
Fluconazole (floo-KON-a-zole)
Prevents and treats certain fungus infections. Belongs to a class of drugs called antifungals.
Brand Name(s):Diflucan
There may be other brand names for Fluconazole.
When Fluconazole Should Not Be Used:
You should not use Fluconazole if you have had an allergic reaction to fluconazole or other similar medicines such as itraconazole (Sporanox®), ketoconazole (Nizoral®), or voriconazole (Vfend®). Do not use Fluconazole if you are receiving cisapride (Propulsid®) or terfenadine (Seldane®).
How to Use Fluconazole:
Liquid, Tablet
- Your doctor will tell you how much of Fluconazole to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- Shake the oral liquid well just before each use. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
- You may take Fluconazole with or without food.
- Keep using Fluconazole for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.
If a dose of Fluconazole is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of Fluconazole:
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The mixed oral liquid should be kept in the refrigerator or at room temperature and used within 14 days. Do not freeze.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid While Taking Fluconazole:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are using a diabetes medicine that you take by mouth (such as glipizide, glyburide, tolbutamide, Diabeta®, Glucotrol®, or Orinase®), cimetidine (Tagamet®), zidovudine (Retrovir®), astemizole (Hismanal®), isoniazid (Nydrazid®), midazolam (Versed®), phenytoin (Dilantin®), rifabutin (Mycobutin®), rifampin (Rifadin®, Rimactane®), valproic acid (Depakene®), or a blood thinner (such as warfarin, Coumadin®). Tell your doctor if you are also using cyclosporine (Gengraf®, Neoral®, Sandimmune®), tacrolimus (Prograf®), theophylline (Theo-Dur®), or birth control pills.
Warnings While Using Fluconazole:
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or heart disease. Tell your doctor if you have cancer or HIV/AIDS.
- Stop using Fluconazole and check with your doctor right away if you or your child have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem.
- Fluconazole may rarely cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Stop taking Fluconazole and call your doctor right away if you or your child have a rash, itching, hives, hoarseness, trouble with breathing, trouble with swallowing, or any swelling of your hands, face, or mouth while you are using Fluconazole.
- Serious skin reactions can rarely occur during treatment with Fluconazole. Check with your doctor right away if you or your child start having a skin rash, itching, or any other skin changes while you are using Fluconazole.
- Fluconazole can rarely cause changes in heart rhythms, such as a condition called QT prolongation. It may change the way your heart beats and cause fainting or serious side effects in some patients. Check with your doctor right away if you or your child have any symptoms of heart rhythm problems, such as fast, pounding, or uneven heartbeats.
- Your doctor will need to check your progress at regular visits while you are using Fluconazole. Be sure to keep all appointments. Blood tests may be needed to check for unwanted effects.
- If your symptoms do not improve or if they get worse, call your doctor.
Possible Side Effects While Using Fluconazole:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
- Blistering, peeling, or red skin rash.
- Dark-colored urine or pale stools.
- Dry mouth, increased thirst, or muscle cramps.
- Nausea, vomiting, loss of appetite, or pain in your upper stomach.
- Swelling in your hands, ankles, or feet.
- Unusual bleeding, bruising, or weakness.
- Yellowing of your skin or the whites of your eyes.
If you notice these less serious side effects while taking Fluconazole, talk with your doctor:
- Diarrhea.
- Headache or dizziness.
- Mild nausea or stomach pain.
If you notice other side effects that you think are caused by Fluconazole, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
